"You are weak. Why are you weak? Because you lack ... hatred." - Itachi to Sasuke
"Why is it that the Uchiha clan was known by all and feared by all? I'll show you what the Sharingan can do when it's wielded by a true heir of the bloodline." - Itachi to Kakashi
"Foolish little brother, if you wish to kill me, hate me, detest me, and survive in an unsightly way. Run, run and cling to life. And one day, when you have the same eyes as I do, come before me." - Itachi to Sasuke
"People live their lives bound by what they accept as correct and true. That's how they define "reality". But what does it mean to be "correct" or "true"? Merely vague concepts ... their "reality" may all be a mirage. Can we consider them to simply be living in their own world, shaped by their beliefs?" - Itachi to Sasuke
"In the world of the Tsukuyomi, I control time and space. For the next seventy-two hours." - Itachi to Kakashi
"We are brothers. That is a unique bond. I am the barrier you must overcome, so you and I will continue to exist together, even if you hate me. That's what being a big brother means." - Itachi to Sasuke
"I've lost all hope for this pathetic clan." - Itachi to Uchiha's
"You are not even worth killing." - Itachi to Sasuke
"Sorry, Sasuke ... this is the last time." - Itachi's last word to Sasuke
"The clan, the clan! You overestimate your own abilities, with no idea